We cannot provide technical support for the Macintosh Operating System, but we have Macintosh drivers for the CP2102 USB-to-UART Bridge Controller that we have tested on Mac OS X 10.7. The drivers should work on Mac OS 10.5 through 10.7. You can download these drivers here: 48014_SiLabsUSBDriverDisk.zip (1MB zip).
Additionally, we have older drivers that other customers have used successfully on both PowerPC- and Intel-based Macs running OS X version 10.3.9 or later, but these probably will not work on version 10.7 or later. You can download these drivers here: OSX_cp2102_drivers.dmg (723k dmg)
Mac OS X compatibility: We have confirmed that our CP2102-based devices work on Mac OS X 10.7 and other customers have used them successfully on older versions. We can assist with advanced technical issues, but most of our tech support staff does not use Macs, so basic support for Mac OS X is limited.